The Universe Orb is an item that spawns every 4200 seconds or 70 minutes with a 1 in 4 chance or 25%.
This can be confused for Cursed Orb, so don't get too excited when you see a black transparent sphere because it's not that good lol hi meow
C-Moon > Reality Moon
Star Platinum OVA Over Heaven > Galaxy Annihilator
King Crimson > King Crimson Alternate Universe